LINC02261

Across TCGA patient cohorts, LINC02261 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,606 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LINC02261-associated GO terms across cancer lineages are Signal transduction in response to DNA damage, Nuclear-transcribed mRNA poly(A) tail shortening, and Negative regulation of gene expression, epigenetic. Each is linked with LINC02261 in more than 12 cancer types. Because this analysis shows association rather than direction, both LINC02261-to-partner and partner-to-LINC02261 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Signal transduction in response to DNA damage grouped by LINC02261-low versus LINC02261-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC02261→partner) and Y-score (partner→LINC02261) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Signal transduction in response to DNA damage →	+0.098	+0.129	<.001	<.001	3	13
ESCA	Nuclear-transcribed mRNA poly(A) tail shortening →	+0.056	+0.111	<.001	<.001	3	12
STAD	Negative regulation of gene expression, epigenetic →	+0.099	+0.152	<.001	<.001	3	12
STAD	Positive regulation of DNA metabolic process →	+0.100	+0.127	<.001	<.001	3	12
ESCA	Vesicle localization →	+0.053	+0.117	.005	<.001	2	13
STAD	Positive regulation of post-translational protein modification →	+0.104	+0.144	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,606 associations by consensus.

Signal transduction in response to DNA damage by LINC02261 expression — STAD

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