Across TCGA pan-cancer cohorts, LINC02258 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of LINC02258’s most consistent transcriptional readouts.
The strongest signal is observed in thyroid carcinoma (THCA), where LINC02258 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC02258 is over-expressed in tumor.
THCA are the cancer types where LINC02258 tumor–normal differential expression is most reproducible.