LINC02240

Across TCGA pan-cancer cohorts, LINC02240 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of LINC02240’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where LINC02240 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC02240 is over-expressed in tumor, although a few such as BRCA show the opposite, repressed pattern.

BRCA, KIRC, and ESCA are the cancer types where LINC02240 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC02240 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	III,IV	−0.178	<.001	6	view →
KIRC	Male	All	+0.020	.020	4	view →
ESCA	All	II,III,IV	+0.130	.022	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

LINC02240–BRCA

Open the BRCA breakdown →