LINC02231

Across TCGA pan-cancer cohorts, LINC02231 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of LINC02231’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where LINC02231 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC02231 is over-expressed in tumor, although a few such as LUSC and LUAD show the opposite, repressed pattern.

LUSC, LUAD, and KIRP are the cancer types where LINC02231 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC02231 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Male	II,III,IV	−0.550	<.001	6	view →
LUAD	Female	II,III,IV	−0.496	<.001	6	view →
KIRP	All	All	−0.044	.004	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

LINC02231–LUSC

Open the LUSC breakdown →