LINC02229

Across TCGA pan-cancer cohorts, LINC02229 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of LINC02229’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC02229 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC02229 is over-expressed in tumor, although a few such as KIRC and KICH show the opposite, repressed pattern.

KIRC, BRCA, and KICH are the cancer types where LINC02229 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC02229 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	II,III,IV	−0.126	<.001	11	view →
BRCA	All	All	+0.063	<.001	6	view →
KICH	Male	All	−0.073	.011	4	view →
HNSC	Male	All	+0.055	.017	3	view →
LUSC	All	III,IV	+0.078	.017	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

LINC02229–KIRC

Open the KIRC breakdown →