LINC02221

Across TCGA patient cohorts, LINC02221 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,168 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LINC02221-associated GO terms across cancer lineages are Signal transduction by p53 class mediator, Regulation of post-translational protein modification, and Regulation of DNA replication. Each is linked with LINC02221 in more than 10 cancer types. Because this analysis shows association rather than direction, both LINC02221-to-partner and partner-to-LINC02221 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Signal transduction by p53 class mediator grouped by LINC02221-low versus LINC02221-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC02221→partner) and Y-score (partner→LINC02221) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Signal transduction by p53 class mediator →	+0.104	+0.082	<.001	<.001	3	11
STAD	Regulation of post-translational protein modification →	+0.111	+0.080	<.001	<.001	3	10
STAD	Regulation of DNA replication →	+0.103	+0.087	<.001	<.001	3	10
STAD	Regulation of DNA repair →	+0.105	+0.093	<.001	<.001	3	10
STAD	Transcription initiation at RNA polymerase II promoter →	+0.107	+0.097	<.001	<.001	3	10
STAD	Mitochondrial membrane organization →	+0.114	+0.088	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,168 associations by consensus.

Signal transduction by p53 class mediator by LINC02221 expression — STAD

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