LINC02214

Across TCGA pan-cancer cohorts, LINC02214 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of LINC02214’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC02214 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC02214 is over-expressed in tumor, although a few such as THCA and BRCA show the opposite, repressed pattern.

KIRC, ESCA, and THCA are the cancer types where LINC02214 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC02214 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	+0.015	.010	4	view →
ESCA	All	II,III,IV	+0.155	.025	2	view →
THCA	Female	All	−0.020	.036	2	view →
BRCA	Female	II,III,IV	−0.016	.016	2	view →
LUAD	Female	II,III,IV	−0.042	.048	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

LINC02214–KIRC

Open the KIRC breakdown →