Across TCGA pan-cancer cohorts, LINC02210-CRHR1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of LINC02210-CRHR1’s most consistent transcriptional readouts.
The strongest signal is observed in thyroid carcinoma (THCA), where LINC02210-CRHR1 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC02210-CRHR1 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.
THCA, BLCA, and LUAD are the cancer types where LINC02210-CRHR1 tumor–normal differential expression is most reproducible.