Across TCGA pan-cancer cohorts, LINC02209 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of LINC02209’s most consistent transcriptional readouts.
The strongest signal is observed in lung adenocarcinoma (LUAD), where LINC02209 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC02209 is over-expressed in tumor.
LUAD, LUSC, and HNSC are the cancer types where LINC02209 tumor–normal differential expression is most reproducible.