LINC02201

Across TCGA pan-cancer cohorts, LINC02201 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of LINC02201’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where LINC02201 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC02201 is over-expressed in tumor, although a few such as KIRC and LUSC show the opposite, repressed pattern.

HNSC, BRCA, and KIRC are the cancer types where LINC02201 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC02201 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	II,III,IV	+0.034	.010	7	view →
BRCA	Female	II,III,IV	+0.141	<.001	6	view →
KIRC	Male	All	−0.020	.001	5	view →
LUSC	Female	All	−0.114	<.001	1	view →
LUAD	All	All	−0.048	.041	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

LINC02201–HNSC

Open the HNSC breakdown →