LINC02197

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LINC02197 mutation is significantly associated with the total protein of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC02197-associated genes across cancer lineages are FOXO3a, c-Jun_pS73, and Di-Ras3. Each is linked with LINC02197 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC02197-to-partner and partner-to-LINC02197 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FOXO3a grouped by LINC02197-low versus LINC02197-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC02197→partner) and Y-score (partner→LINC02197) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECFOXO3a →-0.139-3.156.012.02031
UCECc-Jun_pS73 →-0.210-2.990.016.03621
UCECDi-Ras3 →-0.243-3.169.002.02021
UCECeEF2 →+0.526+3.169.007.02011
UCECEGFR_pY1068 →-0.391-3.169.004.02011
UCECShc_pY317 →-0.301-3.169<.001.02011
Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

FOXO3a by LINC02197 expression — UCEC

Box plot of FOXO3a in LINC02197-low vs LINC02197-high samples in UCEC.

Explore this box plot interactively →

Exploration