LINC02186

Across TCGA pan-cancer cohorts, LINC02186 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of LINC02186’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where LINC02186 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC02186 is over-expressed in tumor, although a few such as BRCA and UCEC show the opposite, repressed pattern.

BRCA, UCEC, and KICH are the cancer types where LINC02186 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC02186 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	III,IV	−0.132	<.001	6	view →
UCEC	All	All	−0.061	.049	2	view →
KICH	All	II,III,IV	−0.024	.032	2	view →
LUSC	All	All	−0.024	.034	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

LINC02186–BRCA

Open the BRCA breakdown →