LINC02185

Across TCGA pan-cancer cohorts, LINC02185 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of LINC02185’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where LINC02185 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC02185 is over-expressed in tumor, although a few such as COAD and BLCA show the opposite, repressed pattern.

COAD, BLCA, and THCA are the cancer types where LINC02185 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC02185 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Male	II,III,IV	−0.562	<.001	11	view →
BLCA	Male	IV	−1.377	<.001	10	view →
THCA	All	III,IV	−0.511	<.001	10	view →
LUAD	Female	III,IV	−2.117	<.001	9	view →
LUSC	All	III,IV	−2.590	<.001	8	view →
LIHC	Male	All	+0.218	<.001	7	view →
BRCA	All	III,IV	−1.502	<.001	6	view →
KICH	All	All	+1.391	<.001	6	view →
UCEC	All	All	−0.439	<.001	6	view →
HNSC	All	IV	−0.442	.012	4	view →
STAD	All	All	−0.429	.001	4	view →
READ	Female	All	−1.080	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

LINC02185–COAD

Open the COAD breakdown →