LINC02180

Across TCGA pan-cancer cohorts, LINC02180 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of LINC02180’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC02180 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC02180 is over-expressed in tumor, although a few such as KIRC and KIRP show the opposite, repressed pattern.

KIRC, KIRP, and BRCA are the cancer types where LINC02180 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC02180 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	IV	−0.085	<.001	12	view →
KIRP	Female	All	−0.113	<.001	9	view →
BRCA	All	III,IV	−0.022	.028	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

LINC02180–KIRC

Open the KIRC breakdown →