LINC02178

Across TCGA pan-cancer cohorts, LINC02178 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of LINC02178’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where LINC02178 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC02178 is over-expressed in tumor, although a few such as KIRC and KICH show the opposite, repressed pattern.

UCEC, LUSC, and BRCA are the cancer types where LINC02178 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC02178 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	All	+0.867	.010	8	view →
LUSC	All	II,III,IV	+0.969	<.001	7	view →
BRCA	Female	II,III,IV	+0.114	.002	6	view →
LUAD	Female	All	+0.206	<.001	5	view →
BLCA	Male	All	+0.995	.028	3	view →
KIRC	All	All	−0.052	.010	3	view →
PAAD	Female	All	+0.370	.002	2	view →
COAD	All	All	+0.303	.017	2	view →
KICH	All	II,III,IV	−0.078	.007	2	view →
HNSC	Female	IV	+1.105	.046	1	view →
THCA	Male	All	+0.048	.039	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

LINC02178–UCEC

Open the UCEC breakdown →