LINC02176

Across TCGA pan-cancer cohorts, LINC02176 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated LINC02176 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher LINC02176 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LINC02176 expression acts as an unfavorable survival marker, although some lineages such as SARC and CESC show a favorable association.

THCA, THYM, and READ are the cancer types where LINC02176 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	OS	Tertile	All	0.733	0.956	<.001	75	view →
THYM	OS	Tertile	All	0.604	0.975	<.001	72	view →
READ	OS	Tertile	II,III,IV	0.111	0.919	<.001	69	view →
SARC	DFS	Tertile	All	0.957	0.590	.001	27	view →
SKCM	OS	Tertile	IV	0.179	0.755	<.001	18	view →
CESC	OS	Tertile	IV	1.000	0.236	.032	18	view →
HNSC	OS	Tertile	IV	0.051	0.642	.001	18	view →
LIHC	OS	Tertile	II,III,IV	0.282	0.798	<.001	18	view →
ESCA	DFS	Median	II,III,IV	0.606	0.431	.020	16	view →
LUSC	DFS	Tertile	All	0.512	0.801	.033	15	view →
UVM	DFS	Tertile	III,IV	0.071	0.636	<.001	9	view →
ACC	DFS	Tertile	IV	0.633	0.129	.028	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

LINC02176–THCA (OS)

Open the THCA breakdown →