LINC02154

Across TCGA pan-cancer cohorts, LINC02154 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of LINC02154’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where LINC02154 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC02154 is over-expressed in tumor, although a few such as LUAD and LUSC show the opposite, repressed pattern.

HNSC, LUAD, and THCA are the cancer types where LINC02154 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC02154 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	IV	+1.851	<.001	12	view →
LUAD	Male	III,IV	−2.913	<.001	9	view →
THCA	All	All	+0.190	<.001	9	view →
KIRC	Male	All	+0.431	<.001	8	view →
COAD	All	II,III,IV	+0.418	<.001	8	view →
BLCA	All	All	+1.446	.008	6	view →
UCEC	All	II,III,IV	+0.283	.001	6	view →
STAD	All	All	+0.278	<.001	6	view →
LUSC	All	All	−1.535	<.001	5	view →
BRCA	All	All	+0.187	.012	4	view →
KIRP	All	All	+0.933	.018	3	view →
KICH	All	All	+0.339	.014	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

LINC02154–HNSC

Open the HNSC breakdown →