LINC02145

Across TCGA patient cohorts, LINC02145 mutation is significantly associated with the total protein of many other genes, with 34 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC02145-associated genes across cancer lineages are eIF4E, FoxM1, and ACC_pS79. Each is linked with LINC02145 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC02145-to-partner and partner-to-LINC02145 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eIF4E grouped by LINC02145-low versus LINC02145-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC02145→partner) and Y-score (partner→LINC02145) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4E →	+0.198	+3.013	.037	.018	3	1
UCEC	FoxM1 →	+0.322	+3.807	.005	<.001	3	1
UCEC	ACC_pS79 →	+0.340	+2.000	.029	.032	3	1
UCEC	GATA6 →	-0.144	-1.992	.038	.031	3	1
UCEC	HSP70 →	-0.432	-3.160	.017	.019	3	1
UCEC	INPP4B →	-0.363	-3.459	.012	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

eIF4E by LINC02145 expression — UCEC

Explore this box plot interactively →