LINC02109

Across TCGA pan-cancer cohorts, LINC02109 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of LINC02109’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where LINC02109 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC02109 is over-expressed in tumor.

HNSC, LUSC, and LUAD are the cancer types where LINC02109 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC02109 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	All	+0.183	<.001	8	view →
LUSC	Female	All	+0.504	<.001	6	view →
LUAD	All	All	+0.203	<.001	6	view →
LIHC	All	All	+0.152	<.001	5	view →
STAD	All	All	+0.275	.005	4	view →
BRCA	Female	All	+0.058	.001	4	view →
BLCA	All	All	+0.239	.049	2	view →
ESCA	All	II,III,IV	+0.065	.049	2	view →
KIRC	All	All	+0.020	.010	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

LINC02109–HNSC

Open the HNSC breakdown →