LINC02079

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LINC02079 mutation is significantly associated with the RNA expression of many other genes, with 2,476 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC02079-associated genes across cancer lineages are PAPLN, CPE, and PSMD9. Each is linked with LINC02079 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC02079-to-partner and partner-to-LINC02079 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PAPLN grouped by LINC02079-low versus LINC02079-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC02079→partner) and Y-score (partner→LINC02079) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECPAPLN →-0.793-3.071<.001<.00132
UCECCPE →-1.141-2.906<.001.00132
UCECPSMD9 →+0.383+2.137<.001.00132
UCECWNT6 →-0.935-2.390.004.00332
UCECATP1B2 →-0.707-2.126.001.00132
UCECENPP2 →-0.793-2.898.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,476 associations by consensus.

PAPLN by LINC02079 expression — UCEC

Box plot of PAPLN in LINC02079-low vs LINC02079-high samples in UCEC.

Explore this box plot interactively →

Exploration