Across TCGA pan-cancer cohorts, LINC02069 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of LINC02069’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where LINC02069 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC02069 is over-expressed in tumor.
HNSC and LUAD are the cancer types where LINC02069 tumor–normal differential expression is most reproducible.