LINC02066

Across TCGA pan-cancer cohorts, LINC02066 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of LINC02066’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where LINC02066 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC02066 is over-expressed in tumor, although a few such as THCA and BRCA show the opposite, repressed pattern.

THCA, BRCA, and HNSC are the cancer types where LINC02066 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC02066 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	II,III,IV	−0.269	<.001	10	view →
BRCA	All	III,IV	−0.813	<.001	6	view →
HNSC	All	II,III,IV	−0.210	.007	4	view →
BLCA	All	IV	−0.091	.026	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

LINC02066–THCA

Open the THCA breakdown →