LINC02058

Across TCGA pan-cancer cohorts, LINC02058 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of LINC02058’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where LINC02058 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC02058 is over-expressed in tumor, although a few such as KIRP and KIRC show the opposite, repressed pattern.

KIRP, KIRC, and KICH are the cancer types where LINC02058 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC02058 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	Male	III,IV	−0.255	<.001	11	view →
KIRC	Male	All	−0.262	<.001	8	view →
KICH	Female	All	−0.295	<.001	7	view →
LUSC	Female	All	−0.190	<.001	6	view →
UCEC	All	All	−0.172	<.001	6	view →
LIHC	All	All	+0.202	.003	5	view →
THCA	All	All	−0.073	<.001	3	view →
HNSC	All	All	−0.052	.035	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

LINC02058–KIRP

Open the KIRP breakdown →