Across TCGA pan-cancer cohorts, LINC02040 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of LINC02040’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC02040 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC02040 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.
KIRC and KICH are the cancer types where LINC02040 tumor–normal differential expression is most reproducible.