Across TCGA pan-cancer cohorts, LINC02020 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of LINC02020’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where LINC02020 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC02020 is over-expressed in tumor.
HNSC are the cancer types where LINC02020 tumor–normal differential expression is most reproducible.