LINC02018

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LINC02018 mutation is significantly associated with the RNA expression of many other genes, with 62 significant associations in total. COAD shows the largest number of these associations.

The most reproducible LINC02018-associated genes across cancer lineages are RNA5SP205, RNA5SP418, and OR6K6. Each is linked with LINC02018 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC02018-to-partner and partner-to-LINC02018 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP205 grouped by LINC02018-low versus LINC02018-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC02018→partner) and Y-score (partner→LINC02018) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNA5SP205 →+0.648+4.267<.001.00932
LUSCRNA5SP418 →+0.595+5.978.003.00232
UCECOR6K6 →+0.170+4.943<.001<.00131
UCECEIF1AY →+0.040+4.789<.001.00131
UCECRNU4-51P →+0.632+3.936<.001.00531
UCECRNU6-1082P →+0.708+5.136<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 62 associations by consensus.

RNA5SP205 by LINC02018 expression — UCEC

Box plot of RNA5SP205 in LINC02018-low vs LINC02018-high samples in UCEC.

Explore this box plot interactively →

Exploration