LINC02005

Across TCGA pan-cancer cohorts, LINC02005 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of LINC02005’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where LINC02005 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC02005 is over-expressed in tumor, although a few such as BRCA and UCEC show the opposite, repressed pattern.

BRCA, UCEC, and COAD are the cancer types where LINC02005 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC02005 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	II,III,IV	−0.519	<.001	6	view →
UCEC	All	All	−0.194	<.001	6	view →
COAD	All	All	+0.227	.001	4	view →
THCA	All	All	−0.027	.002	4	view →
LIHC	Male	All	−0.117	<.001	3	view →
KIRC	Male	III,IV	−0.023	.007	3	view →
LUSC	Male	All	+0.537	<.001	2	view →
CHOL	Female	All	−0.160	.023	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

LINC02005–BRCA

Open the BRCA breakdown →