LINC01999

Across TCGA pan-cancer cohorts, LINC01999 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of LINC01999’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where LINC01999 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01999 is over-expressed in tumor, although a few such as BRCA and LUAD show the opposite, repressed pattern.

KIRP, BRCA, and LUAD are the cancer types where LINC01999 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01999 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	All	II,III,IV	+0.227	<.001	9	view →
BRCA	All	III,IV	−0.109	<.001	6	view →
LUAD	All	III,IV	−0.112	.014	3	view →
KICH	All	All	−0.044	.011	2	view →
THCA	Female	All	−0.037	.011	2	view →
LIHC	Female	All	−0.049	.019	1	view →
KIRC	All	III,IV	+0.047	.043	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

LINC01999–KIRP

Open the KIRP breakdown →