LINC01998

Across TCGA pan-cancer cohorts, LINC01998 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated LINC01998 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher LINC01998 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LINC01998 expression acts as an unfavorable survival marker, although some lineages such as BLCA and ESCA show a favorable association.

HNSC, MESO, and KICH are the cancer types where LINC01998 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	All	0.634	0.755	<.001	89	view →
MESO	DFS	Tertile	All	0.253	0.448	.002	72	view →
KICH	DFS	Median	All	0.680	1.000	.005	59	view →
UVM	OS	Tertile	All	0.305	0.796	.001	45	view →
THCA	OS	Tertile	II,III,IV	0.291	0.960	<.001	45	view →
DLBC	OS	Tertile	III,IV	0.154	0.735	.010	40	view →
BLCA	OS	Tertile	III,IV	0.502	0.199	.008	39	view →
ACC	OS	Tertile	All	0.354	0.666	.008	34	view →
READ	OS	Tertile	III,IV	0.483	0.854	.001	30	view →
KIRP	DFS	Tertile	IV	0.035	0.458	.018	27	view →
STAD	DFS	Quartile	All	0.388	0.640	.004	22	view →
LUSC	DFS	Quartile	II,III,IV	0.498	0.792	.013	20	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

LINC01998–HNSC (DFS)

Open the HNSC breakdown →