Across TCGA pan-cancer cohorts, LINC01986 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of LINC01986’s most consistent transcriptional readouts.
The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where LINC01986 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01986 is over-expressed in tumor, although a few such as LIHC show the opposite, repressed pattern.
LIHC are the cancer types where LINC01986 tumor–normal differential expression is most reproducible.