LINC01970

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, LINC01970 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of LINC01970’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where LINC01970 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01970 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

LUAD, LIHC, and KIRP are the cancer types where LINC01970 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01970 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
LUADMaleAll+0.331<.0018view →
LIHCMaleAll+0.249<.0017view →
KIRPAllII,III,IV+0.250<.0016view →
COADAllII,III,IV+0.138<.0015view →
BLCAAllAll+0.250.0054view →
KICHAllAll−0.194<.0014view →
CHOLAllAll+0.290<.0013view →
LUSCAllAll+0.149.0013view →
UCECAllAll+0.263.0102view →
STADAllAll+0.183.0272view →
PRADAllAll+0.093.0102view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

LINC01970–LUAD

Tumor-vs-normal expression box plot for LINC01970 RNA in LUAD.

Open the LUAD breakdown →

Exploration