Across TCGA pan-cancer cohorts, LINC01965 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of LINC01965’s most consistent transcriptional readouts.
The strongest signal is observed in kidney chromophobe (KICH), where LINC01965 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01965 is over-expressed in tumor, although a few such as KICH and KIRC show the opposite, repressed pattern.
KICH, KIRC, and THCA are the cancer types where LINC01965 tumor–normal differential expression is most reproducible.