Across TCGA pan-cancer cohorts, LINC01953 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of LINC01953’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where LINC01953 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01953 is over-expressed in tumor.
BRCA are the cancer types where LINC01953 tumor–normal differential expression is most reproducible.