Across TCGA pan-cancer cohorts, LINC01928 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of LINC01928’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where LINC01928 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01928 is over-expressed in tumor, although a few such as KIRP and KIRC show the opposite, repressed pattern.
KIRP, KIRC, and KICH are the cancer types where LINC01928 tumor–normal differential expression is most reproducible.