Across TCGA pan-cancer cohorts, LINC01923 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of LINC01923’s most consistent transcriptional readouts.
The strongest signal is observed in colon adenocarcinoma (COAD), where LINC01923 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01923 is over-expressed in tumor, although a few such as COAD and READ show the opposite, repressed pattern.
COAD and READ are the cancer types where LINC01923 tumor–normal differential expression is most reproducible.