Across TCGA pan-cancer cohorts, LINC01922 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of LINC01922’s most consistent transcriptional readouts.
The strongest signal is observed in esophageal carcinoma (ESCA), where LINC01922 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01922 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.
ESCA, THCA, and KIRC are the cancer types where LINC01922 tumor–normal differential expression is most reproducible.