LINC01915

Across TCGA pan-cancer cohorts, LINC01915 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of LINC01915’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where LINC01915 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01915 is over-expressed in tumor, although a few such as LUSC and COAD show the opposite, repressed pattern.

LUSC, COAD, and KIRP are the cancer types where LINC01915 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01915 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	III,IV	−0.773	<.001	9	view →
COAD	Female	II,III,IV	−0.554	<.001	9	view →
KIRP	Male	II,III,IV	−0.144	<.001	9	view →
KIRC	Male	II,III,IV	−0.092	.001	8	view →
READ	All	All	−0.621	<.001	7	view →
KICH	Female	All	−0.347	<.001	7	view →
BLCA	Male	All	−0.660	.005	6	view →
UCEC	All	All	−0.552	<.001	6	view →
BRCA	All	II,III,IV	−0.212	<.001	6	view →
THCA	All	All	−0.092	<.001	5	view →
HNSC	Male	All	−0.116	.009	4	view →
LUAD	Female	III,IV	−0.340	.013	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

LINC01915–LUSC

Open the LUSC breakdown →