Across TCGA pan-cancer cohorts, LINC01903 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of LINC01903’s most consistent transcriptional readouts.
The strongest signal is observed in lung squamous cell carcinoma (LUSC), where LINC01903 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01903 is over-expressed in tumor, although a few such as LUSC and KICH show the opposite, repressed pattern.
LUSC, STAD, and KICH are the cancer types where LINC01903 tumor–normal differential expression is most reproducible.