Across TCGA pan-cancer cohorts, LINC01900 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of LINC01900’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where LINC01900 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01900 is over-expressed in tumor, although a few such as CHOL and THCA show the opposite, repressed pattern.
HNSC, CHOL, and THCA are the cancer types where LINC01900 tumor–normal differential expression is most reproducible.