LINC01887

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, LINC01887 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of LINC01887’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where LINC01887 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01887 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

LUAD, KIRC, and LUSC are the cancer types where LINC01887 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01887 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
LUADAllAll+0.126.0023view →
KIRCMaleAll+0.030.0013view →
LUSCMaleAll+0.235<.0012view →
THCAAllAll−0.115.0262view →
HNSCFemaleII,III,IV+0.079.0172view →
BRCAAllII,III,IV+0.020.0112view →
KIRPMaleAll+0.021.0461view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

LINC01887–LUAD

Tumor-vs-normal expression box plot for LINC01887 RNA in LUAD.

Open the LUAD breakdown →

Exploration