Across TCGA pan-cancer cohorts, LINC01883 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of LINC01883’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where LINC01883 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01883 is over-expressed in tumor, although a few such as BRCA and ESCA show the opposite, repressed pattern.
BRCA, LUSC, and ESCA are the cancer types where LINC01883 tumor–normal differential expression is most reproducible.