Across TCGA pan-cancer cohorts, LINC01874 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of LINC01874’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where LINC01874 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01874 is over-expressed in tumor, although a few such as KIRP and KIRC show the opposite, repressed pattern.

KIRP, KIRC, and KICH are the cancer types where LINC01874 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01874 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	Female	II,III,IV	−4.206	<.001	11	view →
KIRC	Female	All	−2.331	<.001	11	view →
KICH	Male	II,III,IV	−3.282	<.001	8	view →
BRCA	All	III,IV	−0.366	<.001	6	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: LINC01874 RNA expression & survival · all LINC01874 data types