Across TCGA pan-cancer cohorts, LINC01834 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of LINC01834’s most consistent transcriptional readouts.
The strongest signal is observed in thyroid carcinoma (THCA), where LINC01834 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01834 is over-expressed in tumor, although a few such as THCA and PRAD show the opposite, repressed pattern.
THCA and PRAD are the cancer types where LINC01834 tumor–normal differential expression is most reproducible.