LINC01828

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, LINC01828 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of LINC01828’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where LINC01828 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01828 is over-expressed in tumor, although a few such as BLCA and UCEC show the opposite, repressed pattern.

HNSC, BLCA, and UCEC are the cancer types where LINC01828 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01828 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
HNSCAllII,III,IV+0.058.00111view →
BLCAAllAll−0.213.00110view →
UCECAllIII,IV−0.464<.0018view →
KICHAllAll−0.033<.0017view →
COADAllAll−0.049.0104view →
READAllIII,IV−0.095.0442view →
PRADAllAll−0.074.0012view →
BRCAAllIII,IV−0.028.0022view →
LUSCAllIII,IV−0.108.0351view →
STADAllAll−0.096.0181view →
CHOLAllAll+0.090.0231view →
LIHCAllAll+0.017.0491view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

LINC01828–HNSC

Tumor-vs-normal expression box plot for LINC01828 RNA in HNSC.

Open the HNSC breakdown →

Exploration