LINC01827

Across TCGA pan-cancer cohorts, LINC01827 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of LINC01827’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC01827 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01827 is over-expressed in tumor, although a few such as LUAD and LUSC show the opposite, repressed pattern.

KIRC, LUAD, and LUSC are the cancer types where LINC01827 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01827 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	All	+0.382	<.001	11	view →
LUAD	Male	II,III,IV	−0.979	<.001	9	view →
LUSC	Male	III,IV	−1.517	<.001	8	view →
KIRP	Male	All	+0.400	.001	2	view →
HNSC	All	III,IV	+0.183	.031	2	view →
CHOL	All	II,III,IV	−0.164	.008	2	view →
COAD	All	All	+0.048	.019	2	view →
CHOL	All	All	+0.207	.016	1	view →
LIHC	All	All	+0.060	.015	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 8 lineages.

LINC01827–KIRC

Open the KIRC breakdown →