Across TCGA pan-cancer cohorts, LINC01818 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of LINC01818’s most consistent transcriptional readouts.
The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where LINC01818 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01818 is over-expressed in tumor, although a few such as LIHC and CHOL show the opposite, repressed pattern.
LIHC, CHOL, and UCEC are the cancer types where LINC01818 tumor–normal differential expression is most reproducible.