LINC01805

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, LINC01805 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of LINC01805’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where LINC01805 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01805 is over-expressed in tumor, although a few such as HNSC and LUAD show the opposite, repressed pattern.

HNSC, LUAD, and KICH are the cancer types where LINC01805 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01805 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
HNSCAllAll−0.743<.0018view →
LUADFemaleAll−0.155<.0016view →
KICHAllAll−0.031.0085view →
LUSCAllAll+0.429.0012view →
STADAllII,III,IV−0.180.0192view →
KIRPAllAll−0.028.0292view →
LIHCAllII,III,IV+0.018.0401view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

Exploration