Across TCGA pan-cancer cohorts, LINC01804 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of LINC01804’s most consistent transcriptional readouts.
The strongest signal is observed in thyroid carcinoma (THCA), where LINC01804 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01804 is over-expressed in tumor, although a few such as THCA and COAD show the opposite, repressed pattern.
THCA, LUAD, and COAD are the cancer types where LINC01804 tumor–normal differential expression is most reproducible.