Across TCGA pan-cancer cohorts, LINC01789 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of LINC01789’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC01789 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC01789 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.
KIRC, THCA, and KICH are the cancer types where LINC01789 tumor–normal differential expression is most reproducible.