Across TCGA pan-cancer cohorts, LINC01782 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of LINC01782’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC01782 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01782 is over-expressed in tumor, although a few such as KIRC and BRCA show the opposite, repressed pattern.
KIRC, BRCA, and KICH are the cancer types where LINC01782 tumor–normal differential expression is most reproducible.